SetHandler mod_python
PythonPath "sys.path + ['/home/johnny/projects']"

<LocationMatch /downloads>
  PythonHandler mod_deco.downloadshandler
</LocationMatch>

<LocationMatch /screenshots>
  PythonHandler mod_deco.screenshotshandler
</LocationMatch>

<LocationMatch /.*\.[(rst|txt)]>
  PythonHandler mod_deco.resthandler
</LocationMatch>